NEW YORK (AP) — More than 60 CEOs of Minnesota-based companies including Target, Best Buy and UnitedHealth signed an open letter posted on the Minnesota Chamber of Commerce website on Sunday calling for state, local and federal officials to work together, as businesses grapple with how to address tensions in the state and across the country following two fatal shootings by federal agents amid a massive immigration enforcement operation that has spurred protests.

“With yesterday’s tragic news, we are calling for an immediate deescalation of tensions and for state, local and federal officials to work together to find real solutions,” the open letter reads.

CEOs that signed the letter included 3M CEO William Brown, Best Buy CEO Corie Barry, General Mills CEO Jeff Harmening, Target incoming CEO Michael Fiddelke, UnitedHealth Group CEO Stephen Helmsley, and others.

Before the letter, most of the biggest Minnesota-based companies had not issued any public statements about the enforcement surge and unrest.

But the issue has become more difficult to avoid. Over the past two weeks protesters have targeted some businesses they see not taking a strong enough stand against federal law enforcement activity, including Minneapolis-based Target. Earlier in January a Minnesota hotel that wouldn’t allow federal immigration agents to stay there apologized and said the refusal violated its own policies after a furor online.

Meanwhile, the state of Minnesota and the Twin Cities cited devastating economic impacts in a lawsuit filed this month imploring a federal judge to halt the immigration operations. The lawsuit asserted that some businesses have reported sales drops up to 80%.

“In this difficult moment for our community, we call for peace and focused cooperation among local, state and federal leaders to achieve a swift and durable solution that enables families, businesses, our employees, and communities across Minnesota to resume our work to build a bright and prosperous future,” the letter reads.