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5 Best Serums For Mature Skin 2026, Tested & Reviewed

Besides sunscreen, the best serums for mature skin might just be among the most effective skin care products out there. While overhyped formulas certainly exist, experts agree that certain ones can actually make a difference in addressing visible signs of ageing like dark spots, wrinkles, crepiness, and more.

When used regularly and as directed, Dendy Engelman, MD, a board-certified cosmetic dermatologist and Mohs surgeon, confirms, a quality one can make a difference in the appearance of your skin — especially as you get older. “The exact results vary depending on the formula and its ingredients, but many of my patients have seen transformative results — ranging from reduced fine lines and wrinkles to brighter, bouncier and more hydrated skin — when using certain serums,” she says.

To narrow down the hunt for the best serums for mature skin, we asked leading dermatologists, beauty editors, and Glamour contributors to share their all-time favourite products. Our top overall pick is SkinCeuticals CE Ferulic, a bestselling vitamin C serum that protects against free radicals, brightens, reduces the appearance of discolouration, and even helps to soften lines and wrinkles.

Keep scrolling for all the intel on this formula, plus six other options that provide impressive results for sensitive skin, deep wrinkles, and more.


Best Overall: SkinCeuticals C E Ferulic

SkinCeuticals C E Ferulic

Original video from Brigitt Earley testing SkinCeuticals C E Ferulic

  • Pros: Lightweight, fluid-like consistency; tackles tone and texture concerns.
  • Cons: On the expensive side; some reviewers don’t care for its scent.

This little bottle is often dubbed the gold standard of vitamin C serums, thanks to its blend of all-star ingredients and lineup of clinically proven benefits, according to board-certified dermatologist Miriam Hanson, MD. “It combines L-ascorbic acid, vitamin E, and ferulic acid to deliver powerful antioxidant protection,” she says. “It is clinically proven to deliver advanced environmental protection and reduce oxidative damage from UV, ozone, and pollution. It also visibly improves signs of ageing by evening skin tone and boosting firmness, elasticity, and radiance.” It has a lightweight consistency that applies easily to the skin, absorbs quickly, and layers well under moisturiser and sunscreen. While the formula is fragrance-free, some reviewers don’t care for the product’s scent. (However, it’s worth noting that it’s fairly typical for a vitamin C serum to have a slight smell.)

LP Staff Writers

Writers at Lord’s Press come from a range of professional backgrounds, including history, diplomacy, heraldry, and public administration. Many publish anonymously or under initials—a practice that reflects the publication’s long-standing emphasis on discretion and editorial objectivity. While they bring expertise in European nobility, protocol, and archival research, their role is not to opine, but to document. Their focus remains on accuracy, historical integrity, and the preservation of events and individuals whose significance might otherwise go unrecorded.

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