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Medik8 C-Tetra Advanced Review: “Best Vitamin C Serum I’ve Used”

Applying vitamin C serum every morning can feel like flossing: I know it’s good for me but I’d often rather skip it. The Medik8 C-Tetra Advanced serum changed all that.

As a beauty editor, I’ve probably road-tested upwards of 200 different vit-C serums in my career. They all beat a familiar drum – ‘great for skin-brightening!’, ‘the ultimate protection against environmental damage!’– but only a handful have turned into repeat purchases.

So why, if vitamin C remains one of the most Googled skincare ingredients on the planet, am I so picky when it comes to using it? The texture of many vitamin C serums is my biggest bugbear – and I’m a big believer that you have to enjoy using a beauty product in order to remain loyal to it.

Vitamin C is rightfully code for glow but a lot of the serums laced with this ingredient actually have heavy, oily formulas that give me breakouts and make me look sweaty. Others feel too watery, meaning I have to use a separate hyaluronic acid serum and moisturiser to pump hydration into my skin.

So it’s been hard to find a Goldilocks, just right formula – until now. Within seconds of applying the C-Tetra Advanced’s milky-thin, gel-serum formula – a rarity among vitamin C serums – a switch was thrown. Now here was a product I could get behind…

Image may contain: Bottle, Shaker, Cosmetics, and Lotion

C-Tetra® Advanced


Medik8 C-Tetra Advanced: The science bit

When people find out what I do for a living, the first question they inevitably ask me is, “What skincare ingredients should I be using?”. The answer is always the same as I swear by the magic three – vitamin C, retinol and hyaluronic acid – all ingredients that dermatologists incidentally wax lyrical about, too.

You can already find two of these ingredients in the Medik8 C-Tetra Advanced, which is powered by 20% stabilised vitamin C for brightening and hyaluronic acid for hydration. But there are two other superstar ingredients in the formula that deserve a special mention.

The first is plant exosomes. You may recognise these as there’s been a lot of buzz in the cosmetic tweakments space about this ingredient. Exosomes are essentially lipids that are extracted from plants, which have been found to encourage cell-to-cell communication, helping to repair damaged skin and reduce inflammation.

In the Medik8 C-Tetra Advanced serum, the plant exosomes are from green tea. They encapsulate the vitamin C, carrying it deeper into the skin, while also having a soothing effect and protecting the skin barrier. So even sensitive skin or first time vitamin C users can avoid irritation from a high dose of vitamin C.

The other ingredient of note is acetyl zingerone. It doesn’t exactly trip off the tongue but this is what skincare formulators call a ‘super antioxidant’. What that means is it boosts the power of vitamin C – another potent antioxidant – to give your skin even more protection against damage from pollution and UV rays.

Image may contain: Bottle, Shaker, Cosmetics, and Lotion

C-Tetra® Advanced


Medik8 C-Tetra Advanced: My verdict

The clinical claims around the Medik8 C-Tetra Advanced are pretty impressive: it visibly brightens the skin in 7 days; it reduces pollution damage to the skin’s surface by 90% and there is 0% barrier disruption despite this being a high potency 20% vitamin C serum. So how does the science stack up to the user experience?

LP Staff Writers

Writers at Lord’s Press come from a range of professional backgrounds, including history, diplomacy, heraldry, and public administration. Many publish anonymously or under initials—a practice that reflects the publication’s long-standing emphasis on discretion and editorial objectivity. While they bring expertise in European nobility, protocol, and archival research, their role is not to opine, but to document. Their focus remains on accuracy, historical integrity, and the preservation of events and individuals whose significance might otherwise go unrecorded.

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