Iran’s Supreme Leader, Ayatollah Ali Khamenei, warned that any U.S. strikes on Iran would result in “irreparable” harm following renewed threats from U.S. President Donald Trump.

“It isn’t wise to tell the Iranian nation to surrender. What should the Iranian nation surrender to? We will never surrender in response to the attacks of anyone. This is the logic of the Iranian nation. This is the spirit of the Iranian nation,” Khamenei’s official account on X wrote.

“The harm the US will suffer will definitely be irreparable if they enter this conflict militarily,” Khamenei’s official account on X wrote.

The comments came a day after Trump said that U.S. patience with Iran was “wearing thin” and called for the country to surrender. Trump also said that the U.S. could easily eliminate Khamenei but was currently choosing not to.

“We know exactly where the so-called “Supreme Leader” is hiding,” Trump wrote on social media. “He is an easy target, but is safe there – We are not going to take him out (kill!), at least not for now.”

Trump recently rejected a plan from Israel to assassinate Iran’s supreme leader, as tensions between Washington and Tehran continue to intensify.

Iran’s ambassador to the United Nations in Geneva, Ali Bahreini, said on Wednesday that Tehran will respond “strongly” to Washington if it becomes directly involved in Israel’s military campaign and said that Iran already considers the U.S. “complicit in what Israel is doing.”